Just this
morning when I saw an old man who crossed the street but what’s interesting
with this man is that he was holding a long stick as his guide and his eyes
were close. In short, he is blind. I got a bit pity with the man because even
there were huge numbers of vehicles passing the street, he never minded. He crossed
as if he is not blind. Just as much as I want to help him, I didn’t. I hesitated
because I was in hurry plus the people who were also crossing the street
blocked my way. Upon walking, there’s one question popped up on my mind. Why do
some people become blind? And as soon as I want to find answer I made some
brief research.
Blindness
may result from a wide range of conditions, but is most commonly caused by an
eye disease or condition such as glaucoma, diabetic retinopathy, cataract,
age-related macular degeneration and retinitis pigmentosa.
CATARACT
A cataract
is opacity (cloudiness) within the lens. In the treatment of a cataract, the
lens inside the eye is removed and replaced with a clear artificial lens. In
diabetic retinopathy, retinal blood vessels are adversely affected and begin to
leak. Treatment involves photocoagulation with a laser to destroy leaky blood
vessels and to prevent the growth of abnormal blood vessels (angiogenesis). The
actual cloudy appearance of the cataract can be seen through the pupil.
GLAUCOMA
In glaucoma,
the retinal ganglion cells (which send visual information from the retina to
the brain) slowly die over time. The exact cause of this loss is unknown but
frequently high eye (intraocular) pressure is often associated with this
condition. Current treatment is with medications and surgical techniques aimed
at trying to lower intraocular pressure.
ARMD or AMD
The most
common cause of blindness in the aging population is age-related macular
degeneration (ARMD or AMD), which affects over 10 million Americans. ARMD
causes loss of central vision due to the loss of photoreceptors (the
light-sensing cells).This condition is particularly debilitating for the
elderly who may have difficulty walking and remain confined to their homes.
Age-related macular degeneration (ARMD) is a disease that affects the macula -
the area responsible for central and fine detail vision. There are two forms of
the disease: a less severe non-exudative form and the more devastating
exudative form. Clinically, the "wet" form is characterized by the
presence of newly formed blood vessels (subretinal choriodal neovascularization),
exudation and hemorrhages. For some individuals, the "dry" form can
convert and progress into the "wet" form. It is therefore important
that individuals with ARMD have frequent eye examinations.
| blind man |
RP
Retinitis
pigmentosa (RP) affects 1.6 million people worldwide and is the leading cause
of inherited blindness. RP causes a slow and progressive blindness across the
entire visual field. As with ARMD, this disease is associated with
photoreceptor loss. To date, there are no treatments for either ARMD or RP.
Molecular genetic therapy may represent a viable long-range hope although there
are formidable challenges facing this therapeutic approach. It is also
important to keep in mind that even successful repair of genetic function would
only slow or prevent further deterioration rather than restore lost visual function
(as would be possible with prosthesis). Retinitis Pigmentosa (RP) is an
inherited eye condition affecting initially the mid peripheral portion of the
retina. Central vision is generally not affected until the very late stages of
the disease. Clinically, the first observable sign of RP is a narrowing of the
retinal arterioles (small arteries in the retina). Later, retinal pigment
formations known as "bone spicules" and changes in the appearance of
the optic nerve head are apparent.
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